Methyl 5-methyl-4-[(oxomethylene)sulfamoyl]thiophene-3-carboxylate - Names and Identifiers
Methyl 5-methyl-4-[(oxomethylene)sulfamoyl]thiophene-3-carboxylate - Physico-chemical Properties
Methyl 5-methyl-4-[(oxomethylene)sulfamoyl]thiophene-3-carboxylate - Introduction
3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, methyl ester, also known as 3-Thiophenecarboxylic acid isocyanate, chemical formula C9H7NO4S, and is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, methyl ester is yellow or light yellow solid.
-Solubility: Soluble in most organic solvents, such as ethanol, dimethyl sulfoxide, etc.
-Melting point: Depending on the experimental conditions, the melting point range is 80-85 ° C.
-Stability: It can be stored stably under dry, cold and dark conditions, but it may decompose under high light and humidity.
Use:
- 3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, methyl ester is an important intermediate compound commonly used in organic synthesis reactions. It can be used to synthesize drugs, dyes and functional materials containing thiophene structure.
-In organic optoelectronic devices, this compound is also a commonly used light-emitting material.
Method:
3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, the preparation method of methyl ester is more complicated, and a common method is as follows:
1. First, 3-thiophenecarboxylate and 4-isocyanatobenzenesulfonyl chloride are reacted to produce 4-sulfonylphenyl 3-thiophenecarboxylate under alkaline conditions.
2. Then, 3-thiophenecarboxylic acid 4-sulfonylphenyl Ester is reacted with an appropriate amount of methanol to remove the ester to form 3-thiophenecarboxylic acid.
3. Finally, 3-Thiophenecarboxylic acid is reacted with methyl isocyanate under alkaline conditions to form 3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, methyl ester.
Safety Information:
- 3-Thiophenecarboxylic acid, 4-(isocyyanatosulfonyl)-5-methyl-, methyl ester is required to take safety measures when using or operating, including wearing protective glasses, gloves and protective clothing.
-Avoid inhaling dusts, gases or vapors of the compound and avoid contact with skin and eyes. If there is contact, should immediately rinse with plenty of water, and timely medical treatment.
-Store in a closed container, away from fire sources, heat sources and oxidants, etc., to avoid its reaction with flammable and combustible materials.
-Handling and disposal in accordance with relevant local regulations and in compliance with local environmental, health and safety regulations.
Last Update：2024-04-09 21:01:54